(Kaiser Health News) – As the nation grapples with a devastating opioid epidemic, concerns have primarily focused on young people buying drugs on the street. But America’s elderly also have a problem. Over the past several decades, physicians have increasingly prescribed seniors pain medications to address chronic pain from arthritis, cancer, neurological diseases and other illnesses that become more common in later life.
(Medical Xpress) – In a first-in-children randomized clinical study, medical researchers at the University of Maryland School of Medicine (UM SOM) and the Interdisciplinary Stem Cell Institute (ISCI) at the University of Miami Miller School of Medicine have begun testing to see whether adult stem cells derived from bone marrow benefit children with the congenital heart defect hypoplastic left heart syndrome (HLHS). UM SOM surgeons are injecting the cells into the babies’ hearts during open-heart operations at the University of Maryland Medical Center. ISCI is supplying the stem cells for the procedures.
(MIT Technology Review) – Epidermolysis bullosa has been called “the worst disease you’ve never heard of.” Its victims must bandage themselves and suffer unrelenting pain. In the Netherlands, which allows euthanasia, two children have been killed to stop their suffering. Gene therapy offers a possible new way to treat the condition, which in Roeder’s case is due to a DNA mutation that prevents her body from producing type-7 collagen, the material that anchors the upper and lower layers of the skin together.
Medico-Legal Journal (vol. 84, no. 4, 2016) is available online by subscription only.
- “Do Not Resuscitate: Lawful or Unlawful?” by Alec Samuels
- “The State of Ethical-Legal Oaths in UK Medical Practice Today: Is It Time to Look at Standardising?” by RL Atenstaedt
Christian Journal for Global Health (vol. 3, no. 2, 2016) is available online by subscription only.
- “Evaluation of Community Health Worker Training Course Effectiveness in India” by Nicole Butcher, Adeline Sitther, Jachin Velavan, Elizabeth John, Mary
Chandra Thomas, and Nathan Grills
- “A Qualitative Study on Provider Perspectives on the Barriers to Contraceptive Use in Kaliro and Iganga Districts, Eastern Central Uganda” by Constance Sibongile Shumba, Jonathan Miyonga, Judith Kiconco, Patrick Kerchan, and Tonny Tumwesigye
- “A Realist Evaluation of the Formation of Groups of People With Disabilities in Northern India” by Rebekah Young, Matthew Reeve, Alex Devine, Lawrence Singh, and Nathan Grills
- “Maternal and Child Health From a Human Rights Perspective: The Indian Scenario and Nuns as Community Health Enablers” by Dr. Tomi Thomas, Dr. Anto Maliekal
HEC Forum (vol. 28, no. 4, 2016) is available online by subscription only.
- “Models of Ethics Consultation Used by Canadian Ethics Consultants: A Qualitative Study” by Chris Kaposy, Fern Brunger, Victor Maddalena, and Richard Singleton
- “A Qualitative Exploration of a Clinical Ethicist’s Role and Contributions During Family Meetings” by Courtenay R. Bruce, Trevor M. Bibler, Adam M. Pena, and Betsy Kusin
- “Just a Collection of Recollections: Clinical Ethics Consultation and the Interplay of Evaluating Voices” by Virginia L. Bartlett, Mark J. Bliton, and Stuart G. Finder
- “Managing Ethical Difficulties in Healthcare: Communicating in Inter-Professional Clinical Ethics Support Sessions” by Catarina Fischer Grönlund, Vera Dahlqvist, Karin Zingmark, Mikael Sandlund, and Anna Söderberg
- “Failure of the Current Advance Care Planning Paradigm: Advocating for a Communications-Based Approach” by Laura Vearrier
- “Still Human: A Call for Increased Focus on Ethical Standards in Cadaver Research” by Michelle C. Bach
Medicine, Health Care, and Philosophy (vol. 19, no. 4, 2016) is available online by subscription only.
- “The Separation Wall and the Right to Healthcare” by Melania Borgo and Mario Picozzi
- “Rethinking the Ethical Approach to Health Information Management Through Narration: Pertinence of Ricœur’s ‘Little Ethics’” by Corine Mouton Dorey
- “The Near-Failure of Advance Directives: Why They Should Not Be Abandoned Altogether, But Their Role Radically Reconsidered” by Marta Spranzi and Véronique Fournier
- “Uncertainty and Objectivity in Clinical Decision Making: A Clinical Case in Emergency Medicine” by Eivind Engebretsen, Kristin Heggen, Sietse Wieringa, and Trisha Greenhalgh
- “Psychoanalysis and Bioethics: A Lacanian Approach to Bioethical Discourse” by Hub Zwart
- “Organ Donation After Assisted Death: Is It More or Less Ethically-Problematic Than Donation After Circulatory Death?” by Jeffrey Kirby
Ethical Theory and Moral Practice (vol. 19, no. 5, 2016) is available online by subscription only.
- “Disabled – Therefore, Unhealthy?” by Sean Aas
(Reuters) – Colombia’s government has lowered the price of Novartis cancer drug imatinib by nearly half in a bid to cut healthcare costs after failed price negotiations with the Swiss company. Novartis will be legally obliged to sell the drug, which is used to treat leukemia and other cancers, at the new price. The new cost per milligram is 44 percent less than the original price, the Colombian Health Ministry said in a statement late on Tuesday.
(Scientific American) – Thanks to the openness of Caitlyn Jenner and others, public awareness of transgenderism — and demand for trans-specific medical care like counseling, hormone treatments, and genital surgery — is exploding, even for the youngest of patients. At the 30-plus clinics for transgender youth across the US, doctors like Olson-Kennedy can barely keep up with the demand.
(Science Daily) – Social phobia is the most common anxiety disorder of our time. But the current treatment regimen for patients with this diagnosis has not proven very effective. Now a team of Norwegian and British researchers believe they have found a cure for social anxiety disorders. “We’ve set a new world record in effectively treating social anxiety disorders,” says Hans M. Nordahl, a professor of behavioural medicine at the Norwegian University of Science and Technology (NTNU).
(UPI) – A new study by UCLA is calling for routine drug testing in primary care settings in areas where misuse of drugs is prevalent. Researchers found that 19.4 percent of people answering a computerized self-administered survey in community clinics in East Los Angeles admitted to moderate-to-high drug use. In Tijuana, Mexico, that number was 5.7 percent. Both findings were considerably higher than the results from household surveys reported.
(Science Daily) – Nearly half of early stage breast cancer patients considered having double mastectomy and one in six received it — including many who were at low risk of developing a second breast cancer, a new study finds. Many patients who chose double mastectomy demonstrated little knowledge of the lack of benefit this aggressive procedure has for most patients.
(The Globe and Mail) – Is there any place for conscience in medicine? Currently, the technocratic answer is no. If the state says euthanasia is a right, then euthanasia there must be – and it must be provided everywhere, even by faith-based institutions and by groups that have pledged to care for the most vulnerable people in society. Dr. Constant Leung disagrees. He’s a family physician in Vancouver and his specialty is the elderly. He has persuaded hundreds of old, gravely ill people to accept palliative care in their last weeks or months of life.
(Bloomberg BNA) – Any discrepancies in how the FDA and the HHS regulate human subject research must be resolved over the next three years under a new requirement in the 21st Century Cures law. The biomedical innovation law, which President Barack Obama signed Dec. 13 (Pub. L. No. 114-255), seeks to spur development and approval of new drugs and devices to get them to patients more quickly. While much of the conversation on Cures focused on the billions of dollars in new research money, lawmakers also aimed to remove administrative burdens so scientists can spend more time on their research and less time on paperwork.
The New England Journal of Medicine (vol. 375, no. 19, 2016) is available online by subscription only.
- “Meaning and the Nature of Physicians’ Work” by D.I. Rosenthal and A. Verghese
- “Embodying the Three Rs in Fiji” by A. Creaton
Scandinavian Journal of Public Health (vol. 44, no. 8, 2016) is available online by subscription only.
- “Child Mortality and Poverty in Three World Regions (the West, Asia and Sub-Saharan Africa) 1988–2010: Evidence of Relative Intra-Regional Neglect?” by Colin Pritchard and Steven Keen
- “Tracking a Female Foetus: Preventing Gender Imbalance in India” by Neelam Dehal, Kewal Krishan, Amarjeet Singh, and Tanuj Kanchan
- “Changes Over Time in the Risk of Hospitalization for Physical Diseases Among Homeless Men and Women in Stockholm: A Comparison of Two Cohorts”by Ulla Beijer, Daniel Bruce, and Bo Burström
Philosophy, Ethics, and Humanities in Medicine (vol. 11, no. 8, 2016) is available online by subscription only.
- “Informed Consent for the Diagnosis of Brain Death: A Conceptual Argument” by Muramoto O
Nursing Ethics (vol. 23, no. 7, 2016) is available online by subscription only.
- “What Ethics for Case Managers? Literature Review and Discussion” by Aline Corvol, Grégoire Moutel, and Dominique Somme
- “The Moral Courage of Nursing Students Who Complete Advance Directives with Homeless Persons” by Woods Nash, Sandra J Mixer, Polly M McArthur, and Annette Mendola
- “Transplant Tourism and Organ Trafficking: Ethical Implications for the Nursing Profession” by Floraidh AR Corfee
- “Clinical Group Supervision for Integrating Ethical Reasoning: Views from Students and Supervisors” by Karin Blomberg and Birgitta Bisholt
- “Difficult Healthcare Transitions: Ethical Analysis and Policy Recommendations for Unrepresented Patients” by Rosalind Abdool, Michael Szego, Daniel Buchman, Leah Justason, Sally Bean, Ann Heesters, Hannah Kaufman, Bob Parke, Frank Wagner, and Jennifer Gibson
- “Cross-Cultural Validation of the Moral Sensitivity Questionnaire-Revised Chinese Version” by Fei Fei Huang, Qing Yang, Jie Zhang, Qing Hua Zhang, Kaveh Khoshnood, and Jing Ping Zhang
- “Nurses’ Adherence to Ethical Codes: The Viewpoints of Patients, Nurses, and Managers” by Marzieh Momennasab, Afifeh Rahmanin Koshkaki, Camellia Torabizadeh, and Seyed Ziaeddin Tabei
- “Ethical Challenges Related to Next of Kin – Nursing Staffs’ Perspective” by Siri Tønnessen, Betty-Ann Solvoll, and Berit Støre Brinchmann
European Journal of Human Genetics (vol. 24, no. 12, 2016) is available online by subscription only.
- “Role of Pharmacogenetics in Public Health and Clinical Health Care: A SWOT Analysis” by Ritika Kapoor, Wei Chuen Tan-Koi, and Yik-Ying Teo
- “Who Should Have Access to Genomic Data and How Should They be Held Accountable? Perspectives of Data Access Committee Members and Experts” by Mahsa Shabani, Adrian Thorogood, and Pascal Borry
- “Whole-Exome Sequencing in Pediatrics: Parents’ Considerations Toward Return of Unsolicited Findings for Their Child” by Candice Cornelis, Aad Tibben, Wybo Dondorp, Mieke van Haelst, Annelien L Bredenoord, Nine Knoers, Marcus Düwell, Ineke Bolt, and Marieke van Summeren