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We’re Zeroing in on the ‘Holy Grail’ of COVID-19 Immunity

July 21, 2021

(The Atlantic) – In recent weeks, the correlate community has been buzzing louder than ever. Scientists are on the cusp of confidently defining some correlates of protection against symptomatic disease for the COVID-19 vaccines. If confirmed, these correlates could revolutionize the way we tackle SARS-CoV-2 immunization: Vaccine makers testing a new inoculation may no longer need to follow tens of thousands of people for many months to test their product’s protection. Instead, they could inject just a few hundred people, snag some drops of blood, and see if the elusive correlate is met. That’s how we tee up new flu vaccines every year without the rigmarole of gargantuan clinical trials. (Read Full Article)

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How the Delta Variant Achieves Its Ultrafast Spread

July 21, 2021

(Nature) – Since first appearing in India in late 2020, the Delta variant of SARS-CoV-2 has become the predominant strain in much of the world. Researchers might now know why Delta has been so successful: people infected with it produce far more virus than do those infected with the original version of SARS-CoV-2, making it very easy to spread. According to current estimates, the Delta variant could be more than twice as transmissible as the original strain of SARS-CoV-2. (Read Full Article)

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In the Same Health System, Black Patients Are Prescribed Fewer Opioids Than White Patients

July 21, 2021

(STAT News) – Inequities in health care are pervasive, from access to quality of care, and a new study finds that common opioids such as codeine and morphine are more often prescribed to white patients than to Black patients treated within the same health system. White patients received both more pills and stronger doses, according to the study, published Wednesday in the New England Journal of Medicine. In about 90% of the 310 health systems studied, the opioid dose prescribed to white patients was higher than the one prescribed to Black patients. On average, white patients received 36% more pain medication by dosage than Black patients, even though both groups received prescriptions at similar rates. (Read Full Article)

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Unvaccinated Staff Eyed in Rising Nursing Home Cases, Deaths

July 21, 2021

(Associated Press) – Lagging vaccination rates among nursing home staff are being linked to a national increase in COVID-19 infections and deaths at senior facilities, and are at the center of a federal investigation in a hard-hit Colorado location where disease detectives found many workers were not inoculated. The investigation by the Centers for Disease Control and Prevention of facilities in the Grand Junction, Colorado, area raises concerns among public health doctors that successes in protecting vulnerable elders with vaccines could be in peril as the more aggressive delta variant spreads across the country.  (Read Full Article)

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Drug Distributors, J&J Reach $26 Billion Opioid Settlement

July 21, 2021

(Axios) – The three dominant prescription drug distributors — AmerisourceBergen, Cardinal Health and McKesson — and Johnson & Johnson have agreed to pay a combined amount of $26 billion to settle allegations that they fueled the country’s opioid crisis. Why it matters: The companies, which have admitted no wrongdoing, are paying a sum of money that equates to 4% of their combined annual revenue. Meanwhile, a record 70,000 Americans died from opioid overdoses during the pandemic in 2020. (Read Full Article)

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‘Dealing with a Different Beast’: Why Delta Has Doctors Worried

July 21, 2021

(Medscape) – Catherine O’Neal, MD, an infectious disease physician, took to the podium of the Louisiana governor’s press conference on July 16 and did not mince words. “The delta variant is not last year’s virus, and it’s become incredibly apparent to healthcare workers that we are dealing with a different beast,” she said. Louisiana is one of the least vaccinated states in the country. In the United States as a whole, 48.6% of the population is fully vaccinated. In Louisiana, it’s just 36%, and Delta is bearing down. (Read Full Article)

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‘Speech Neuroprosthesis’ Gives Voice to a Man Who Couldn’t Speak

July 20, 2021

(Medscape) – A “speech neuroprosthesis” that translates brain signals into words that appear on a screen has helped a man with severe paralysis, who had lost the ability to speak, communicate in sentences. It’s believed to be the first time words and sentences were decoded directly from cortical activity during attempted speech from someone who is paralyzed and cannot speak. (Read Full Article)

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States Are Sitting on Millions of Surplus Covid-19 Vaccine Doses as Expiration Dates Approach

July 20, 2021

(STAT News) – Millions of unused Covid-19 vaccines are set to go to waste as demand dwindles across the United States and doses likely expire this summer, according to public health officials. Several state health departments told STAT they have repeatedly asked the federal government to redistribute their supply to other countries, many of which are facing a third wave of the Covid-19 pandemic. Officials in Washington have rejected those requests, citing legal and logistical challenges. (Read Full Article)

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China Moves to Ease Child-Rearing Costs, in Drive to Boost Births

July 20, 2021

(Wall Street Journal) – China said it would ease financial burdens and social restrictions associated with child-rearing, seeking to encourage births as it loosens decades-old rules on family planning. China said that it would reduce the cost of raising and educating children and shore up labor protections for women over the next five years, according to a policy document drafted by China’s ruling Communist Party and its cabinet, which was published Tuesday by the state-run Xinhua News Agency. (Read Full Article)

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Virus Slams Cuba as It Races to Roll Out Its New Vaccines

July 20, 2021

(ABC News) – The COVID-19 pandemic is slamming Cuba like never before, even as the country races to roll out its homegrown vaccines — the only locally developed shots being widely used in Latin America. The island had seen far fewer infections that most other Latin American nations over the first year or so of the disease, imposing strict quarantines, isolating the infected and shutting down its tourism industry despite devastating economic consequences. (Read Full Article)

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India’s Pandemic Death Toll Could Be in the Millions

July 20, 2021

(Associated Press) – India’s excess deaths during the pandemic could be a staggering 10 times the official COVID-19 toll, likely making it modern India’s worst human tragedy, according to the most comprehensive research yet on the ravages of the virus in the South Asian country. Most experts believe India’s official toll of more than 414,000 dead is a vast undercount, but the government has dismissed those concerns as exaggerated and misleading. The report released Tuesday estimated excess deaths — the gap between those recorded and those that would have been expected — to be 3 million to 4.7 million between January 2020 and June 2021. It said an accurate figure may “prove elusive” but the true death toll “is likely to be an order of magnitude greater than the official count.” (Read Full Article)

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US Opioid Lawsuits on Verge of Settlements with 4 Companies

July 20, 2021

(Associated Press) – The yearslong effort by state and local governments in the U.S. to force the pharmaceutical industry to help pay to fix a nationwide opioid addiction and overdose crisis took a major step forward Tuesday when lawyers for local governments announced they were on the verge of a $26 billion settlement with the nation’s three biggest drug distribution companies and the drugmaker Johnson & Johnson. (Read Full Article)

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Third Covid Wave Upends Fragile South Africa, a Warning for Developing World

July 20, 2021

(Wall Street Journal) – Wave after wave of coronavirus is pummeling South Africa’s fragile economy and its largely unvaccinated population, creating a spiral of death, lockdowns and anger that has fueled the country’s worst rioting since the collapse of white minority rule in 1994. At least 215 people died in the violence across South Africa’s two most populous provinces, and more than 3,400 have been arrested. While the looting had quieted by Monday, the situation remains tense in parts of the country.  (Read Full Article)

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COVID Leaves Wake of Medical Debt Among US Adults

July 20, 2021

(Medscape) – About one third of US adults struggled with medical debt during the pandemic, according to data from a Commonwealth Fund survey released July 16. Despite the passage of four major relief bills in 2020 and 2021 and federal efforts to offset pandemic- and job-related coverage loss, many people continued to face financial challenges, especially those with a low income and those who are Black or Latino. (Read Full Article)

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Unvaccinated Americans Are Behind Rising Covid-19 Hospitalizations

July 19, 2021

(Wall Street Journal) – The vast majority of patients driving up Covid-19 hospitalizations in parts of the U.S. are unvaccinated, according to hospitals, some of which are reactivating surge plans used in the peak of the pandemic. As the highly contagious Delta variant spreads nationwide, some hospital and public-health officials said they are preparing for hospitalizations to potentially reach new pandemic peaks where fewer people are vaccinated. (Read Full Article)

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Cleveland Clinic’s About-Face on the New Alzheimer’s Drug

July 19, 2021

(Axios) – Before the Cleveland Clinic said it would not administer Aduhelm, the new FDA-approved Alzheimer’s drug, the hospital system was promoting the unproven drug on its social media accounts. Why it matters: Cleveland Clinic was the first major medical center to say it would not use Aduhelm, and two hospital systems have followed the clinic’s lead. But the abrupt change could confuse patients, who were told less than two weeks ago by the clinic that the drug offered “hope.” (Read Full Article)

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Emergency Medicine’s Original Sin

July 19, 2021

(The Atlantic) – The misconception that emergency medics provide transportation, not medicine, leaves them to cope with all sorts of indignities. “They’re used to being second-class citizens,” says Michael Levy, the president of the National Association of EMS Physicians. In one hour—during which they may respond to several 911 calls—the median paramedic or EMT makes a little more than $17. That’s half the hourly pay of registered nurses and less than one-fifth the pay of doctors—if they’re paid at all. During the pandemic, emergency medics were literally enclosed in rolling boxes with COVID-19 patients. But in some states, they were not prioritized alongside other essential health-care workers for the first round of vaccines. After delivering their precious cargo to a hospital, in many cases they don’t learn the final diagnosis, or whether their patient ever makes it back home. (Read Full Article)

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The Latest: CDC Leader: US in ‘Pandemic of the Unvaccinated’

July 16, 2021

(Associated Press) – The director of the Centers for Disease Control and Prevention says the COVID-19 outbreak in the U.S. is becoming “a pandemic of the unvaccinated.” Speaking during a White House briefing, Dr. Rochelle Walensky says cases in the U.S. are up about 70% over the last week, hospital admissions are up 36% and deaths rose by 26%. Nearly all hospital admissions and deaths, she says, are among the unvaccinated. (Read Full Article)

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Germany Floods: ‘My City Looks Like a Battlefield’

July 16, 2021

(BBC) – Germans have shared their horror at the speed with which floodwaters engulfed their homes and businesses, devastating many areas near the River Rhine. Some compare the scale of devastation with the pounding that Germany endured in World War Two. And in a reminder of the war, the Germany army is using armoured vehicles to help clear away debris. In the village of Schuld, in the Eifel region, the flash flood ripped buildings apart and tossed cars over, filling the streets with debris and thick layers of mud. (Read Full Article)

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African Countries to Receive First U.S. Donated COVID-19 Vaccines in Days–Gavi

July 16, 2021

(Reuters) – Nearly 50 African countries are to receive 25 million COVID-19 vaccine doses donated by the United States, with the first shipments to Burkina Faso, Djibouti and Ethiopia in coming days, U.S. officials and the Gavi vaccine alliance said on Friday. (Read Full Article)

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